02264nas a2200313   4500008004100000022001400041245006000055210005700115260001300172300001000185490001600195520138500211653001501596653002601611653001201637653001101649653002701660653002401687653001101711653001801722653001901740653001401759653002801773653003201801100002301833700002001856700001501876856005901891       2011                        eng d  a1879-347900aGestational diabetes screening: the low-cost algorithm.0 aGestational diabetes screening the lowcost algorithm  c2011 Nov  aS30-30 v115 Suppl 13 a<p>The American Diabetes Association has endorsed the demanding recommendation by the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) that every pregnant woman should undergo the oral glucose tolerance test (OGTT) for the screening of gestational diabetes mellitus (GDM). The aim of this study was to find out if the fasting plasma glucose (FPG) and newer emerging technologies could simplify the cumbersome IADPSG algorithm. Two FPG thresholds (of the OGTT) were used to rule in and rule out GDM in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) cohort (n = 23316) and a population at high risk for GDM (n = 10283). For the HAPO cohort and the high-risk population, respectively, FPG thresholds of: (a) ≥ 5.1 mmol/L (specificity 100%) independently ruled in GDM in 1769 (8.3%) women and 2975 (28.9%) women; and (b) ≤ 4.4 mmol/L ruled out GDM in 11526 (49.4%) women (84.1% sensitivity) and 2228 (21.7%) women (95.4% sensitivity). Use of the FPG independently could have avoided 13295 (57.0%) and 5203 (50.6%) OGTTs in the 2 groups. The initial FPG-by significantly reducing the number of cumbersome OGTTs needed-can make the IADPSG recommendations more acceptable worldwide. The number of GDM women missed is population dependent. For low-resource countries, alternative newer and cheaper tests in development hold an exciting future.</p>10aAlgorithms10aDiabetes, Gestational10aFasting10aFemale10aGlucose Tolerance Test10aGuidelines as Topic10aHumans10aHyperglycemia10aMass Screening10aPregnancy10aPregnancy Complications10aSensitivity and Specificity1 aAgarwal, Mukesh, M1 aWeigl, Bernhard1 aHod, Moshe  uhttp://www.microfluidicsciences.com/drupal/?q=node/208